Diosmin Phospholipid Complex – High-Load Phospholipid Complex

Diosmin is a flavone glycoside semi-synthesised from citrus hesperidin and well known in venous support. Its very low solubility makes phospholipid complexation useful for dispersibility. It is valued in leg comfort and circulation formulas.

High-load phospholipid complex: a higher active-to-phospholipid ratio for smaller serving sizes with enhanced bioavailability.

GUTINS Diosmin Phospholipid Complex — high-load phospholipid complex is offered for manufacturers, formulators and brands. Specification: Active assay + phospholipid ratio declared; form / technology: high-load phospholipid complex; diet suitability: Verify lecithin source.

Product Specifications

Key Benefits

• Supports healthy venous tone
• Supports leg comfort and lightness
• Supports healthy microcirculation
• Pairs with hesperidin in classic flavonoid fractions
• Phospholipid carrier supports bioavailability

Uses & Applications

Typical applications: Capsules, tablets, sachets.

• Vein and leg comfort capsules
• Circulation tablets
• Women's wellness formulas
• Travel comfort supplements
• Combination formulas with horse chestnut and rutin
• Sachets for elderly users

How to Use / Dosage

• Typical daily intake: 300-600 mg/day of complex (diosmin commonly 450-900 mg/day)
• Typical use level: 10-60% in capsule fills and tablets; 1-5% in sachets and powders
• Formulation tip: Ideal where capsule space is limited; dose on active equivalent declared on the CoA.
• Weigh accurately and pre-blend small quantities with a carrier (e.g. maltodextrin, MCC or rice flour) for uniform distribution.
• Final dosage should be based on the lot-specific Certificate of Analysis, the target serving size and the rules of your destination market.

Solubility & Formulation

Lipid-compatible; disperses in water with agitation better than the uncomplexed active; partly soluble in ethanol. Parent active: dispersible in water and warm liquids; soluble to partly soluble in ethanol and oils; phospholipid matrix improves wetting versus the plain extract

Storage & Handling

Store sealed in a cool (below 25 °C), dry place away from light and oxygen; nitrogen-flushed packs preferred; reseal promptly. Keep container tightly closed; use clean, dry utensils. Shelf life is typically 24 months in unopened original packaging (see CoA).

Regulatory Note

Diosmin is a medicine in several EU countries at therapeutic doses; food supplement use depends on national rules. US dietary ingredient status should be verified. Phospholipid complex forms may be treated as new ingredients in some markets; confirm the status of the complexed form and lecithin source before launch.

Diet suitability: Verify lecithin source. This product is supplied as a raw ingredient for further manufacturing and is not a finished consumer product. The buyer is responsible for ensuring the ingredient, its use level and all label claims comply with the regulations of the destination market (e.g. FDA, EFSA, FSSAI, Health Canada, TGA).

Caution & Disclaimer

• May cause GI upset, headache or dizziness
• Possible interaction with drugs metabolised by CYP enzymes
• Not recommended in pregnancy or lactation without advice
• Contains phosphatidylcholine - confirm soy or sunflower lecithin origin for allergen labelling

For manufacturing, formulation and professional use only. Not for direct consumption in concentrated form. Keep out of reach of children. Avoid inhalation of dust and contact with eyes; use suitable PPE when handling. Consult a qualified healthcare professional before use if pregnant, nursing, taking medication or managing a medical condition. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Bulk & Wholesale Orders

Need more than 5 Kg, a custom specification, private label support or documentation (CoA, TDS, SDS, allergen and GMO statements)? Contact the GUTINS team for bulk pricing and lead times.