Diosmin Powder – Micronized Diosmin (Citrus-derived)

Diosmin is a flavone glycoside produced by dehydrogenation of citrus-derived hesperidin. It is widely used in vein health formulas to support venous tone, lymphatic flow and leg comfort; micronized grades offer improved dispersion.

Supplied as a standardized botanical extract powder with a declared marker-compound assay for batch-to-batch consistency.

GUTINS Diosmin Extract — micronized diosmin is offered for manufacturers, formulators and brands. Specification: micronized diosmin; form / technology: Standardized extract; diet suitability: Plant-based.

Product Specifications

Key Benefits

• Supports healthy venous tone
• Supports lymphatic circulation
• Supports leg comfort and lightness
• Supports capillary integrity
• Works synergistically with hesperidin

Uses & Applications

Typical applications: Circulation.

• Micronized diosmin-hesperidin tablets
• Vein and leg comfort capsules
• Circulation support formulas
• Travel leg comfort supplements
• Post-partum and pregnancy-adjacent leg formulas (with medical guidance)

How to Use / Dosage

• Typical daily intake: 450-1,000 mg/day of diosmin (often as 90% diosmin/10% hesperidin)
• Typical use level: 30-90% in tablet and capsule fills
• Formulation tip: Standardized extracts are best dosed on the basis of the marker assay stated on the CoA.
• Weigh accurately and pre-blend small quantities with a carrier (e.g. maltodextrin, MCC or rice flour) for uniform distribution.
• Final dosage should be based on the lot-specific Certificate of Analysis, the target serving size and the rules of your destination market.

Solubility & Formulation

Practically insoluble in water, ethanol and oils; soluble in dilute alkali and DMSO

Storage & Handling

Store tightly closed in a cool, dry place (below 25 °C) away from light and moisture.. Keep container tightly closed; use clean, dry utensils. Shelf life is typically 24 months in unopened original packaging (see CoA).

Regulatory Note

Diosmin is a medicinal active in several EU countries and may be treated as a medicinal substance there; it is sold as a dietary ingredient in the US. Verify classification in the destination market.

Diet suitability: Plant-based. This product is supplied as a raw ingredient for further manufacturing and is not a finished consumer product. The buyer is responsible for ensuring the ingredient, its use level and all label claims comply with the regulations of the destination market (e.g. FDA, EFSA, FSSAI, Health Canada, TGA).

Caution & Disclaimer

• Registered as a medicine in some countries - check product classification
• May cause GI upset, headache or dizziness
• May interact with drugs metabolized by CYP enzymes
• Use in pregnancy only under professional guidance
• Very low water solubility - requires good mixing

For manufacturing, formulation and professional use only. Not for direct consumption in concentrated form. Keep out of reach of children. Avoid inhalation of dust and contact with eyes; use suitable PPE when handling. Consult a qualified healthcare professional before use if pregnant, nursing, taking medication or managing a medical condition. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Bulk & Wholesale Orders

Need more than 5 Kg, a custom specification, private label support or documentation (CoA, TDS, SDS, allergen and GMO statements)? Contact the GUTINS team for bulk pricing and lead times.