Home /L-Proline Powder – Fermentation-Derived

L-Proline Powder – Fermentation-Derived

L-Proline is a non-essential amino acid that, with hydroxyproline and glycine, forms the backbone of collagen. It is used in skin, joint and connective tissue formulas and in cosmetics as a humectant. Fermentation-derived grades are suitable for vegan positioning.

GUTINS L-Proline — fermentation-derived is offered for manufacturers, formulators and brands. Specification: fermentation-derived; form / technology: Powder; diet suitability: Vegetarian where process permits.

Product Specifications

Product L-Proline — fermentation-derived
Category Amino Acids & Derivatives
Subcategory Amino acids / sports
Base Ingredient / Source L-Proline
Scientific Name (2S)-pyrrolidine-2-carboxylic acid
Specification / Assay fermentation-derived
Form / Technology Powder
Source Type Fermentation / synthesis
Diet Suitability Vegetarian where process permits
INCI Name Proline
CAS Number 147-85-3
EINECS / EC Number 205-702-2
Solubility Very soluble in water (about 1,500 g/L at 25 °C); soluble in ethanol; insoluble in oils
Trend / Positioning Core amino acid
Available Pack Sizes 50 g, 225 g, 1 Kg, 5 Kg (larger volumes on request)
Documentation CoA, TDS and SDS available on request

Key Benefits

  • Key building block of collagen
  • Supports skin firmness and elasticity
  • Supports joint and connective tissue health
  • Supports wound-healing nutrition
  • Natural humectant for skin

Uses & Applications

Typical applications: Sports nutrition, cognition, recovery.

  • Collagen support powders
  • Skin, hair and nail supplements
  • Joint health formulas
  • Vegan collagen-builder blends
  • Skincare moisturizers
  • Clinical nutrition

How to Use / Dosage

  • Typical daily intake: 500-3,000 mg/day
  • Typical use level: 2-20% in collagen and joint blends; 0.1-2% in cosmetics
  • Weigh accurately and pre-blend small quantities with a carrier (e.g. maltodextrin, MCC or rice flour) for uniform distribution.
  • Final dosage should be based on the lot-specific Certificate of Analysis, the target serving size and the rules of your destination market.

Solubility & Formulation

Very soluble in water (about 1,500 g/L at 25 °C); soluble in ethanol; insoluble in oils

Storage & Handling

Store tightly closed in a cool, dry place below 25 °C, protected from moisture and light.. Keep container tightly closed; use clean, dry utensils. Shelf life is typically 24 months in unopened original packaging (see CoA).

Regulatory Note

Listed as a nutrient/food ingredient (US 21 CFR 172.320 permits amino acids as food additives with limits); widely used in EU food supplements and sports foods. Verify source (fermentation vs. animal-derived) declarations and limits in the destination market.

Diet suitability: Vegetarian where process permits. This product is supplied as a raw ingredient for further manufacturing and is not a finished consumer product. The buyer is responsible for ensuring the ingredient, its use level and all label claims comply with the regulations of the destination market (e.g. FDA, EFSA, FSSAI, Health Canada, TGA).

Caution & Disclaimer

  • Generally well tolerated
  • Caution with hyperprolinaemia and kidney disease
  • Very hygroscopic - keep tightly sealed
  • Not recommended in pregnancy and lactation at supplemental doses

For manufacturing, formulation and professional use only. Not for direct consumption in concentrated form. Keep out of reach of children. Avoid inhalation of dust and contact with eyes; use suitable PPE when handling. Consult a qualified healthcare professional before use if pregnant, nursing, taking medication or managing a medical condition. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Bulk & Wholesale Orders

Need more than 5 Kg, a custom specification, private label support or documentation (CoA, TDS, SDS, allergen and GMO statements)? Contact the GUTINS team for bulk pricing and lead times.

Specification

SKUGUT-AMI-0328-50G
TypeAmino Acids & Derivatives
benefitJoint & Bone
benefitSkin & Hair
collectionAmino Acids
dietVegetarian
formPowder
formatPowders & Sachets
ingredientL-Proline
menuProteins & Amino Acids
sourceFermentation
sourceSynthetic / Nature-Identical
trendCore Range

Usage

Typical dosage 0.1–0.5%. Adjust to application and heat process.