Tributyrin – Delayed-Release Matrix Powder

Tributyrin is a triglyceride composed of three butyric acid units, found naturally in butter. It acts as a stable butyrate prodrug that releases butyrate through lipase activity along the intestine.

Delayed-release matrix powder engineered to protect the active through the stomach and support release further along the gut.

GUTINS Tributyrin — delayed-release matrix powder is offered for manufacturers, formulators and brands. Specification: active assay + encapsulation efficiency; form / technology: delayed-release matrix powder; diet suitability: Verify carrier.

Product Specifications

Key Benefits

• Butyrate delivery with lower odour
• Supports gut barrier integrity
• Supports colon health
• Postbiotic SCFA support
• Available as liquid or carrier powder

Uses & Applications

Typical applications: Premixes, gummies, sachets, tablets, beverages.

• Softgels and liquid capsules
• Gut health capsules
• Postbiotic stacks
• Functional foods
• Animal feed additives

How to Use / Dosage

• Typical daily intake: 300–1,000 mg/day
• Typical use level: 10–70% in capsules (liquid 90% in softgels); 0.1–0.5% in feed
• Formulation tip: Avoid milling or high-shear processing that could compromise the release matrix.
• Weigh accurately and pre-blend small quantities with a carrier (e.g. maltodextrin, MCC or rice flour) for uniform distribution.
• Final dosage should be based on the lot-specific Certificate of Analysis, the target serving size and the rules of your destination market.

Solubility & Formulation

Matrix limits dissolution in acidic media; disperses at intestinal pH. Parent active: liquid is poorly soluble in water; miscible with oils and ethanol; powder grades dispersible in water

Storage & Handling

Store sealed in a cool, dry place below 25 °C, protected from light, oxygen and humidity.. Keep container tightly closed; use clean, dry utensils. Shelf life is typically 24 months in unopened original packaging (see CoA).

Regulatory Note

Tributyrin is a US GRAS flavouring substance (FEMA) and sold as a dietary ingredient; EU food supplement status should be verified (flavouring use permitted). Verify in the destination market.

Diet suitability: Verify carrier. This product is supplied as a raw ingredient for further manufacturing and is not a finished consumer product. The buyer is responsible for ensuring the ingredient, its use level and all label claims comply with the regulations of the destination market (e.g. FDA, EFSA, FSSAI, Health Canada, TGA).

Caution & Disclaimer

• Bitter taste in liquid form
• Mild GI changes possible
• Carrier in powder grades may contain allergens
• Limited data in pregnancy and breastfeeding

For manufacturing, formulation and professional use only. Not for direct consumption in concentrated form. Keep out of reach of children. Avoid inhalation of dust and contact with eyes; use suitable PPE when handling. Consult a qualified healthcare professional before use if pregnant, nursing, taking medication or managing a medical condition. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Bulk & Wholesale Orders

Need more than 5 Kg, a custom specification, private label support or documentation (CoA, TDS, SDS, allergen and GMO statements)? Contact the GUTINS team for bulk pricing and lead times.