Nattokinase – 20,000 FU/g Concentrate

Nattokinase is a serine protease produced by Bacillus subtilis var. natto, the bacterium used to make the Japanese fermented soy food natto. It is valued in cardiovascular formulas for supporting healthy circulation and normal fibrinolytic activity.

Enzyme powder with a declared activity (units per gram) for digestive and systemic enzyme formulas.

GUTINS Nattokinase — 20,000 FU/g concentrate is offered for manufacturers, formulators and brands. Specification: 20,000 FU/g concentrate; form / technology: Enzyme powder; diet suitability: Varies.

Product Specifications

Key Benefits

• Supports healthy circulation
• Supports normal fibrinolytic activity
• Supports cardiovascular wellness
• Supports healthy blood pressure already within normal range
• Standardised in fibrin units (FU)

Uses & Applications

Typical applications: Digestive formulas, functional foods, specialty supplements.

• Circulation and heart health capsules
• Nattokinase + serrapeptase systemic enzymes
• Travel circulation formulas
• Softgels with K2-free natto extract
• Healthy aging cardiovascular blends
• Enteric-coated tablets

How to Use / Dosage

• Typical daily intake: 2,000–4,000 FU/day (e.g. 100–200 mg of 20,000 FU/g)
• Typical use level: 5–40% in capsule/tablet fills (enteric preferred); 0.5–2% in softgels
• Formulation tip: Dose on activity units, not weight; keep processing temperatures low.
• Weigh accurately and pre-blend small quantities with a carrier (e.g. maltodextrin, MCC or rice flour) for uniform distribution.
• Final dosage should be based on the lot-specific Certificate of Analysis, the target serving size and the rules of your destination market.

Solubility & Formulation

Water-soluble / dispersible; activity is sensitive to heat, moisture and extreme pH.

Storage & Handling

Store sealed at 2–8 °C or below 25 °C in a dry place; keep away from moisture and heat to preserve activity.. Keep container tightly closed; use clean, dry utensils. Shelf life is typically 24 months in unopened original packaging (see CoA).

Regulatory Note

Sold as a dietary ingredient in the US (NDI notifications on file); EU status is not established as a food supplement ingredient and may require Novel Food authorisation. Verify in the destination market.

Diet suitability: Varies. This product is supplied as a raw ingredient for further manufacturing and is not a finished consumer product. The buyer is responsible for ensuring the ingredient, its use level and all label claims comply with the regulations of the destination market (e.g. FDA, EFSA, FSSAI, Health Canada, TGA).

Caution & Disclaimer

• Increases bleeding risk with anticoagulants, antiplatelets, NSAIDs or fish oil at high doses
• Stop at least 2 weeks before surgery; avoid in bleeding disorders
• Soy-derived – check allergen status; specify vitamin K2-free if needed
• Not for use in pregnancy or breastfeeding

For manufacturing, formulation and professional use only. Not for direct consumption in concentrated form. Keep out of reach of children. Avoid inhalation of dust and contact with eyes; use suitable PPE when handling. Consult a qualified healthcare professional before use if pregnant, nursing, taking medication or managing a medical condition. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Bulk & Wholesale Orders

Need more than 5 Kg, a custom specification, private label support or documentation (CoA, TDS, SDS, allergen and GMO statements)? Contact the GUTINS team for bulk pricing and lead times.