Vitamin K2 MK-7 – Direct-Compression Grade

Vitamin K2 MK-7 – Direct-Compression Grade

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Menaquinone-7 is a long-chain vitamin K2 form, produced by fermentation (Bacillus subtilis natto) or synthesis in the all-trans configuration. Its long half-life makes it the leading K2 form for bone and cardiovascular formulas.

Direct-compression grade engineered for flow and compressibility, suitable for tablet manufacture without wet granulation.

GUTINS Vitamin K2 MK-7 — direct-compression grade is offered for manufacturers, formulators and brands. Specification: application-grade specification; form / technology: direct-compression grade; diet suitability: Verify carrier.

Product Specifications

Product Vitamin K2 MK-7 — direct-compression grade
Category Formulation-Grade Ingredients
Subcategory Application-optimized grades
Base Ingredient / Source Vitamin K2 MK-7
Scientific Name Menaquinone-7
Specification / Assay application-grade specification
Form / Technology direct-compression grade
Source Type Ingredient-specific
Diet Suitability Verify carrier
CAS Number 2124-57-4
Solubility Insoluble in water; soluble in oils; powder and dispersible grades are water-dispersible
Trend / Positioning Formulation-ready
Available Pack Sizes 50 g, 225 g, 1 Kg, 5 Kg (larger volumes on request)
Documentation CoA, TDS and SDS available on request

Key Benefits

  • Contributes to maintenance of normal bones
  • Contributes to normal blood clotting
  • Supports healthy calcium utilisation
  • Long half-life for once-daily dosing
  • Synergistic with vitamin D3

Uses & Applications

Typical applications: Tablets, powders, beverages, gummies.

  • D3 + K2 softgels and capsules
  • Bone-health tablets
  • Heart-health formulas
  • Liquid drops and sprays
  • Gummies and chewables
  • Fortified foods and beverages

How to Use / Dosage

  • Typical daily intake: 45–200 µg/day
  • Typical use level: Microgram-dosed: 0.5–5% of 0.2–2% powders in tablets and capsules; ppm level in beverages
  • Formulation tip: Blend with standard lubricants (e.g. 0.5–1% magnesium stearate) and compress directly.
  • Weigh accurately and pre-blend small quantities with a carrier (e.g. maltodextrin, MCC or rice flour) for uniform distribution.
  • Final dosage should be based on the lot-specific Certificate of Analysis, the target serving size and the rules of your destination market.

Solubility & Formulation

Insoluble in water; soluble in oils; powder and dispersible grades are water-dispersible

Storage & Handling

Store below 15–25 °C in sealed, light-protective containers under nitrogen where possible; avoid heat, moisture and oxygen.. Keep container tightly closed; use clean, dry utensils. Shelf life is typically 24 months in unopened original packaging (see CoA).

Regulatory Note

Menaquinone (MK-7) is authorised as a vitamin K form for EU food supplements; marketed as a dietary ingredient in the US with GRAS notices for some sources. Verify spec and source-specific authorisation in the destination market.

Diet suitability: Verify carrier. This product is supplied as a raw ingredient for further manufacturing and is not a finished consumer product. The buyer is responsible for ensuring the ingredient, its use level and all label claims comply with the regulations of the destination market (e.g. FDA, EFSA, FSSAI, Health Canada, TGA).

Caution & Disclaimer

  • Can reduce the effect of warfarin and other vitamin K antagonists
  • Specify all-trans content – cis isomers are less active
  • Sensitive to light and alkaline minerals (e.g. magnesium oxide) – use protected grades
  • Check carrier (MCC, starch, oil) for dietary status

For manufacturing, formulation and professional use only. Not for direct consumption in concentrated form. Keep out of reach of children. Avoid inhalation of dust and contact with eyes; use suitable PPE when handling. Consult a qualified healthcare professional before use if pregnant, nursing, taking medication or managing a medical condition. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Bulk & Wholesale Orders

Need more than 5 Kg, a custom specification, private label support or documentation (CoA, TDS, SDS, allergen and GMO statements)? Contact the GUTINS team for bulk pricing and lead times.

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